Publications

Patient experiences with prenatal cell‐free DNA screening in a safety net setting   
Kirsten Riggan, Amelia Barwise, Jane Q. Yap, Niamh Condon, Megan Allyse. Prenatal Diagnosis.

Grounded in Reality: Integrating Community Values and Priorities of End Users in Human Gene Editing
Kirsten Riggan et al. American Journal of Bioethics.

Parents of children with Down syndrome reflect on their postnatal diagnoses, 2003-2022
Jonathan Artel et al. American Journal of Medical Genetics.

The impact of implicit and explicit bias about disabilities on parent experiences and information provided during prenatal screening and testing Meredith S., Weiss S., Kleinert H., Tyrrell C. Disability and Health Journal.

Translational Justice in Human Gene Editing: Bringing End User Engagement and Policy Together
Megan Allyse et al. American Journal of Bioethics.

Views of parents of children with Down syndrome on Alzheimer’s disease vaccination
Sarah Batbold et al. Journal of Intellectual Disabilities.

Never “totally prepared”: Support groups on helping families prepare for a child with a genetic condition
Kaitlynn P Craig et al. Journal of Community Genetics.

Recommendations to Improve the Patient Experience and Avoid Bias When Prenatal Screening/Testing
Stephanie Meredith et al.. Disability and Health Journal.

Beyond Abortion Clinics: How Overturning Roe Will Obstruct Life-Saving Research and Fetal Therapy
Marsha Michie. The American Journal of Bioethics.

Prenatal genetics in a post-Roe United States
Megan Allyse, Marsha Michie. Cell Reports Medicine.

The Impact of Telehealth on the Delivery of Prenatal Care During COVID-19: A Mixed Methods Study of Barriers and Opportunities to Improve Healthcare Communication in Discussions about Pregnancy and Prenatal Genetic Testing
Ruth Farrell et al. JMIR Formative Research.

Considering Reprogenomics in the Ethical Future of Fetal Therapy Trials
Ruth Farrell, Marsha Michie. The American Journal of Bioethics.

What Really Matters Now in Prenatal Genetics
Marsha Michie, Megan Allyse. The American Journal of Bioethics.

Born Well: Prenatal Genetics and the Future of Having Children
Megan Allyse, Marsha Michie. Springer Nature.

Pregnant Women in Trials of COVID‐19: A Critical Time to Consider Ethical Frameworks of Inclusion in Clinical Trials
Ruth Farrell, Marsha Michie, Rachel Pope. Ethics and Human Research.

Is preparation a good reason for prenatal genetic testing? Ethical and critical questions
Marsha Michie. Birth Defects Research.

Evaluating the Risks and Benefits of Genetic and Pharmacologic Interventions for Down Syndrome: Views of Parents
Kirsten A Riggan et al. The American Journal of Intellectual and Developmental Disabilities.

Prioritizing Women’s Health in Germline Editing Research
Ruth M. Farrell et al. The AMA Journal of Ethics.

The personal utility of cfDNA screening: Pregnant patients’ experiences with cfDNA screening and views on expanded cfDNA panels
Ruth M. Farrell et al. The Journal of Genetic Counseling.

Attitudes Toward Hypothetical Uses of Gene-Editing Technologies in Parents of People with Autosomal Aneuploidies
Ericka Snure Beckman et al. The CRISPR Journal.

The clinical application of gene editing: ethical and social issues
Kelly E. Ormond et al. Personalized Medicine.

Response to Johansen Taber et al.
Brian Skotko et al. Genetics in Medicine.

Adherence of cell-free DNA non-invasive prenatal screens to ACMG recommendations
Brian Skotko et al. Genetics in Medicine.

What do we do now?: Responding to claims of germline editing in humans
Megan Allyse et al. Genetics in Medicine.

Weaponizing Hope: Sources of Hope, Unrealistic Optimism, and Denial
Marsha Michie, Megan Allyse, Katie A Stoll, Zubin Master. The American Journal of Bioethics.

Gene Modification Therapies: Views of Parents of People with Down Syndrome
Marsha Michie, Megan Allyse. Genetics in Medicine.

Conflicts of Interest in Genetic Counseling: Persistent Underlying Questions
Katie A Stoll, Amanda Mackinson, Megan A Allyse, Marsha Michie. Genetics in Medicine.

Offering Prenatal Screening in the Age of Genomic Medicine: A Practical Guide
Megan A Allyse et al. Journal of Women’s Health.

Is Mitochondrial Donation Germ‐Line Gene Therapy? Classifications and Ethical Implications
Ainsley J Newson, Anthony Wrigley. Bioethics.

Conflicts of interest in genetic counseling: acknowledging and accepting.
Katie A Stoll, Amanda Mackison, Megan A Allyse and Marsha Michie. Genetics in Medicine.

Expanding Use of cfDNA Screening in Pregnancy: Current and Emerging Ethical, Legal, and Social Issues
Lindsay Parham, Marsha Michie, Megan Allyse. Current Genetics Medicine Reports.

Providing Unrestricted Access to Prenatal Testing Does Not Translate to Enhanced Autonomy
Vardit Ravitsky, Francois Rousseau & Anne-Marie Laberge. American Journal of Bioethics.

Modern Pregnancies and (Im)Perfect Babies
Stephanie A. Kraft. American Journal of Bioethics

Dr. Pangloss’s Clinic: Prenatal Whole Genome Sequencing and a Return to Reality
Megan Allyse, James P. Evans & Marsha Michie. American Journal of Bioethics.

Mandating Moral Reflection?
Jessica Mozersky & Pamela Sankar. American Journal of Bioethics.

Clinical implementation of NIPT: Understanding the role of non-specialist provider education
Subhashini Chandrasekharan; Subarna Pradhan; Anthony Hung; Mary Anne McDonald. Prenatal Diagnosis. 

Barriers to clinical adoption of next generation sequencing: Perspectives of a policy Delphi panel
Donna A. Messner, Jennifer Al Naber, Pei Koay, Robert Cook-Deegan, Mary Majumder, Gail Javitt, Patricia Deverka, Rachel Dvoskin, Juli Bollinger, Margaret Curnutte, Subhashini Chandrasekharan, Amy McGuire. Applied and Translational Genomics.

Sequenom v. Ariosa — The Death of a Genetic Testing Patent
Robert Cook‑Deegan and Subhashini Chandrasekharan. New England Journal of Medicine.

Non-invasive Prenatal Testing and the Unveiling of an Impaired Translation Process
Murdoch, B., Ravitsky, V., et al. Journal of Obstetrics and Gynaecology Canada.

With Rapid Uptake of Noninvasive Prenatal Screening, Many Question its Impact on Abortion
Heger, M. GenomeWeb.

Impact of the increased adoption of prenatal cfDNA screening on non-profit patient advocacy organizations in the United States.
Meredith, S, Kaposy, C, Miller V.J., Allyse, M.A., Chandrasekharan, S, Michie, MM, and the Prenatal Testing PAG Coalition. Prenatal Diagnosis

Informed decision-making about prenatal cfDNA screening: As assessment of written materials.
Michie, M, Kraft, S.A., Minear, M.A., Ryan, R.R., Allyse, M.A. In press. Ethics, Medicine & Public Health: Special Issue: Ethics, Medicine and Genetics.

“I think we’ve got too many tests!”: Prenatal providers’ reflections on ethical and clinical challenges in the practice integration of cell-free DNA screening.
Gammon, B, Kraft, S.A., Michie, M.M., Allyse, M.A. In press. Ethics, Medicine & Public Health: Special Issue: Ethics, Medicine and Genetics.

Experiences of Mandarin-speaking and English-speaking women of undergoing non-invasive prenatal genetic screening.
Li, G. D. and Allyse, M.A. In press. Ethics, Medicine & Public Health: Special Issue: Ethics, Medicine and Genetics.

Noninvasive Prenatal Screening (NIPS) for Fetal Aneuploidies. (Book chapter)
Allyse M.A., Highsmith W.E. Jr., Borowski K.S., Wick M.J. Diagnostic Molecular Pathology.

“The Top Priority Is a Healthy Baby”: Narratives of Health, Disability, and Abortion in Online Pregnancy Forum Discussions in the US and China.
Li G, Chandrasekharan S, Allyse M. Journal of Genetic Counseling.

Non-invasive prenatal testing in the non-Western context.
Vardit Ravitsky, Jessica Mozersky, Marsha Michie, Rayna Rapp, Megan Allyse, and Subhashini Chandrasekharan. BioNews.

Non-Invasive Prenatal Testing (NIPT): Identifying Key Clinical, Ethical, Social, Legal and Policy Issues.
Vardit Ravitsky. Nuffield Council on Bioethics.

Beyond the Genetic Diagnosis: Providing Parents What They Want to Know
Robert A. Saul and Stephanie Hall Meredith. Pediatrics in Review. 

The use of noninvasive prenatal testing in obstetric care: educational resources, practice patterns, and barriers reported by a national sample of clinicians.
Ruth M. Farrell, Patricia K. Agatisa, Mary Beth Mercer, Ariane G. Mitchum, Marissa B. Coleridge. Prenatal Diagnosis.

Non-invasive prenatal testing for fetal chromosome abnormalities: review of clinical and ethical issues.
Jean Gekas, Sylvie Langlois, Vardit Ravitsky, François Audibert, David Gradus van den Berg, Hazar Haidar, and François Rousseau. Applications of Clinical Genomics.

Will Personal Genomic Information Transform One’s Self?
Fishman, J and McGowan, M. Barbara Prainsack, Silke Schicktanz (eds). Genetics as Social Practice: Transdisciplinary Views on Science and Culture.

Beyond the Genetic Diagnosis: Providing Parents What They Want to Know.
Saul RA, Meredith SH. Pediatr Rev.

Being Human: The Ethics, Law, and Scientific Progress of Genome Editing.
Newson, A and Wrigley, A. Australian Quarterly.

Genomic Testing in The Paediatric Population: Ethical Considerations in Light of Recent Policy Statements.
Ainsley J. Newson, Lisa Schonstein. Molecular Diagnosis and Therapy.

Embryology policy: Revisit the 14-day rule.
Insoo Hyun, Amy Wilkerson and Josephine Johnston. Nature.

Online direct-to-consumer messages about non-invasive prenatal genetic testing.
Farrell R, Agatisa PK, Mercer M, Smith MB. Reproductive Biomedicine & Society Online.

Non-Invasive Prenatal Testing: Review of Ethical, Legal and Social Implications
Haidar H, Dupras C, Ravitsky V. BioéthiqueOnline.

The Down Syndrome Information Act: Balancing the Advances of Prenatal Testing Through Public Policy.
Leach M. Intellectual and Developmental Disabilities.

Spanish-and English-Speaking Pregnant Women’s Views on cfDNA and Other Prenatal Screening: Practical and Ethical Reflections.
E Floyd, MA Allyse, M Michie. Journal of Genetic Counseling.

The Age of Unreason: A review of Embryos Under the Microscope by Jane Maienschein.
Allyse M. 2016. American Journal of Bioethics.

“This lifetime commitment”: Public narratives of disability and non-invasive prenatal genetic testing.
Steinbach R, Michie M, Allyse M, Liu E and Cho MK. Accepted. American Journal of Medical Genetics Pt A. 

Cherchez la femme: Reproductive CRSPR and Women’s Choices.
Allyse M, Michie M, Mozersky J and Rapp R. 2015. American Journal of Bioethics.

Prudentia Populo: Involving the community in biobank research.
Allyse M, McCormick J and Sharp R. 2015. American Journal of Bioethics.

Global perspectives on clinical adoption of NIPT.
Minear MA, Lewis C, Pradhan S, Chandrasekharan S. Prenatal Diagnosis. 35: 10, 959–967

Too Much, Too Soon? Commercial Provision of Non-Invasive Prenatal Testing for Sub-Chromosomal Abnormalities and Beyond.
Allyse M and Chandrasekharan S. 2015. Genetics and Medicine. 

Noninvasive Prenatal Genetic Testing: Current And Emerging Ethical, Legal, And Social Issues.
Minear MA, Alessi S, Allyse M, Michie M, Chandrasekharan S. 2015. Annu. Rev. Genomics Hum. Genet, 16.

Hoping Someday Never Comes: Deferring Ethical Thinking about Non-Invasive Prenatal Testing.
Mozersky, J. In Press. AJOB Empirical Bioethics. 

Old Questions, New Paradigms: Ethical, Legal and Social Complications of Non-Invasive Prenatal Testing.
Michie, M and Allyse, M. In Press. AJOB Empirical Bioethics.

“Don’t want no risk, don’t want no problems”: Public understandings of the risks and benefits of novel prenatal technologies in the United States.
Allyse M, Sayres LC, Michie M, Goodspeed T and Cho M. In Press. AJOB Empirical Bioethics.

Non-invasive prenatal testing: a review of international implementation and challenges.
Allyse M, Minear MA, Berson E, Sridhar S, Rote M, Hung A, Chandrasekharan S. International Journal of Women’s Health 7, 113.

 Trustworthy Research Institutions: The Challenging Case of Studying the Genetics of Intelligence.
Johnston J, Banerjee MP and Geller G. 2015. Hastings Center Report.

Reducing Rate of Fertility Multiples Requires Policy Changes.
Johnston J, Gusmano MK, and Patrizio P. 2015. JAMA Pediatrics.

Is There Room for Not Knowing ‘Everything’?
Johnston J. 2015. Hastings Center Report

Findings of Nonparentage: A Case for Autonomy
Michie M, Allyse M. Pediatrics 135 (1), e284-e285

Conflicts of interest and effective oversight of assisted reproduction using donated oocytes
Valarie K Blake, Michelle L McGowan, Aaron D Levine. The Journal of Law, Medicine & Ethics

Non-Invasive Prenatal Testing: A review of international implementation and challenges
M Allyse, MA Minear, E Berson, S Sidhar, M Rote, A Hung, S Chandrasekharan. 2014. International Journal of Women’s Health.

Noninvasive Prenatal Testing Goes Global
S Chandrasekharan, MA Minear, A Hung, M Allyse. 2014. Science Translational Medicine 6 (231), 231fs15-231fs15

Attitudes towards non-invasive prenatal testing for aneuploidy among US adults of reproductive age
M Allyse, LC Sayres, TA Goodspeed, MK Cho. 2014. Journal of Perinatology 34 (6), 429-434

Do recent US Supreme Court rulings on patenting of genes and genetic diagnostics affect the practice of genetic screening and diagnosis in prenatal and reproductive care?
Subhashini Chandrasekharan, Amy L. McGuire, Ignatia B. Van den Veyver. 2014. Prenatal Diagnosis.

Demographic and Experiential Correlates of Public Attitudes Towards Cell-Free Fetal DNA Screening
LC Sayres, M Allyse, TA Goodspeed, MK Cho. 2014. Journal of Genetic Counseling, 1-11

In Search of Real Autonomy for Fertility Patients. Johnston J, Gusmano MK, and Patrizio P. 2014. Health Economics, Policy and Law

Preterm Births, Multiples, and Fertility Treatment. Johnston J, Gusmano MK, and Patrizio P. 2014. Fertility and Sterility

Best ethical practices for clinicians and laboratories in the provision of noninvasive prenatal testing
MA Allyse, LC Sayres, M Havard, JS King, HT Greely, L Hudgins, J Taylor, K Ormond. 2013. Prenatal Diagnosis 33 (7), 656-661

Commercial landscape of noninvasive prenatal testing in the United States
Ashwin Agarwal, Lauren C Sayres, Mildred K Cho, Robert Cook-Deegan and Subhashini Chandrasekharan. 2013. Prenatal Diagnosis.

Imperfect informed consent for prenatal screening: Lessons from the Quad screen
ML Constantine, M Allyse, M Wall, R De Vries, TH Rockwood. 2013. Clinical Ethics.

Why We Should All Pay for Fertility Treatment. Johnston J and Gusmano MK. 2013. Hastings Center Report

The NIH Stem Cell Registry: An Absence of Gamete Donor Consent. Wilkerson A, Wongsatittham K and Johnston J. 2013. Cell Stem Cell

Cell-free fetal DNA testing for fetal aneuploidy and beyond: clinical integration challenges in the US context
M Allyse, LC Sayres, JS King, ME Norton, MK Cho. 2012. Human Reproduction 27 (11), 3123-3131

Integrating stakeholder perspectives into the translation of cell-free fetal DNA testing for aneuploidy
LC Sayres, M Allyse, MK Cho. 2012. Genome Medicine, 4 (6), 49

Translating cell-free fetal DNA technology: structural lessons from non-invasive RhD blood typing
TA Goodspeed, M Allyse, LC Sayres, ME Norton, MK Cho. 2012. Trends in Biotechnology 31 (1), 7-9

In the public interest?
LC Sayres, M Allyse, TA Goodspeed, MK Cho. 2012. Science Translational Medicine 4 (144), 144fs23-144fs23

Normalizing Atypical Genitalia: How a Heated Debate Went Astray. Johnston J. 2012. Hastings Center Report.

Cell‐free fetal DNA testing: a pilot study of obstetric healthcare provider attitudes toward clinical implementation
LC Sayres, M Allyse, ME Norton, MK Cho. 2011. Prenatal Diagnosis 31 (11), 1070-1076