This study examined understanding of results, clinical follow-up and decisional regret in women who had received a false positive result from a noninvasive cfDNA screening test. Women were recruited through online pregnancy forums and interviewed by telephone.
Women overwhelmingly report that they do not consider they made an informed decision regarding undergoing cfDNA screening. Many felt that if they had known about the potential for a false positive before agreeing to testing they may have made a different testing decision. Alternately, they might have received a high-risk result differently, knowing that the possibility of a false positive existed.
Papers from this study:
Gammon E, Jaramillo C and Allyse M. (Submitted) Decisional Regret in Women Receiving High-Risk or Inconclusive Results from Non-Invasive Prenatal Genetic Screening. Prenatal Diagnosis.
Presentations from this study:
Decisional Regret in Women Receiving High-Risk or Inconclusive Results from Non-Invasive Prenatal Genetic Screening. 2016. Annual Meeting of the International Society for Prenatal Diagnosis. Berlin, Germany.
The effects of delivery context on women’s experiences of prenatal cfDNA screening: A tale of two studies. 2017. American College of Medical Genetics Annual Clinical Genetics Meeting. Phoenix, AZ. [Download PDF here]